Women's Health Weekly
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Breast Cancer
New findings in breast cancer described from Keimyung University
April 24th, 2008
"Matrix metalloproteinase-9 (MMP-9) plays an important role in the invasion and metastasis of cancer cells. In this study, we examined the inhibitory effect of capillarisin, a bioactive flavonoid of Artemisia capillaries, on phorbol myristate acetate (PMA)-induced MMP-9 expression in MCF-7 human breast carcinoma cells," scientists writing in the journal Biochemical and Biophysical Research Communications report. "Capillarisin significantly and selectively suppressed PMA-induced MMP-9 expression in MCF-7 and the Matrigel invasion assay showed that capillarisin reduces PMA-induced invasion of MCF-7 cells. Capillarisin has been found to suppress PMA-induced MMP-9...
Source: Women's Health Weekly (2008-04-24)
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