Women's Health Weekly
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of Women's Health Weekly
We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.
Breast Cancer
Reports from University of Regensburg add new data to research in breast cancer
April 24th, 2008
"The estrogen receptor (ER) expression and HER2 amplification are important factors in determining the prognosis and therapy of breast cancer. Interactions between the two signaling pathways for example resulted in ER alpha-dependent regulation of HER2 expression in breast cancer cells," researchers in Regensburg, Germany report. "In this study, we investigated to what extent ERss is able to affect the HER2 expression. For this purpose, we analyzed HER2 levels in ERss1-overexpressing clones of the breast cancer cell lines MCF-7 and SK-BR-3 and of the ovarian cancer cell lines SK-OV-3 and OVCAR-3 by both RT-PCR and Western blot analysis. Treatment with ligand 17-ss...
Source: Women's Health Weekly (2008-04-24)
|
