Women's Health Weekly
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Breast Cancer
Research from Baylor College of Medicine, College of Medicine provide new insights into breast cancer
April 24th, 2008
"Previously, we had identified gene expression patterns that predicted response to neoadjuvant docetaxel. Other studies have validated that a high Recurrence Score (RS) by the 21-gene RT-PCR assay is predictive of worse prognosis but better response to chemotherapy," researchers in the United States report. "We investigated whether tumor expression of these 21 genes and other candidate genes can predict response to docetaxel. Core biopsies from 97 patients were obtained before treatment with neoadjuvant docetaxel (4 cycles, 100 mg/m(2) q3 weeks). Three 10-mu m FFPE sections were submitted for quantitative RT-PCR assays of 192 genes that were selected from our previous...
Source: Women's Health Weekly (2008-04-24)
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