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Women's Health Weekly

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Breast Cancer



Research reports on breast cancer from Fudan University provide new insights



April 24th, 2008

" Associated with many molecules, metastasis includes cell adhesion to extracellular matrix, migration towards specific direction and invasion into local vessel of distant organs. The purpose of the present study was to evaluate the role of ecto-5'-nucleotidase (eN, ecto-5-NT, CD73) generated extracellular adenosine in biologically malignant behaviors of human breast cancer cell lines," scientists in Shanghai, People's Republic of China report.

"Materials and methods Two human breast cancer cell lines, T-47D with lower expression of CD73 and MB-MDA-231 with higher expression of CD73, were used to investigate the functions of CD73. The effects of CD73 over-expression on...


Source: Women's Health Weekly (2008-04-24)

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