Women's Health Weekly
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Breast Cancer
Research results from W.S. Rubinstein and colleagues update understanding of breast cancer
April 24th, 2008
According to a study from the United States, "BRCA1 and BRCA2 breast cancers have distinct biological features as evidenced by histopathologic, immunohistochemical, gene expression profiling, and array-comparative genomic hybridization data. BRCA1 breast cancers may have a worse prognosis but may, however be amenable to treatment such as chemotherapy for small high-grade, lymph node negative breast cancers." "Paradoxically, tamoxifen may provide effective adjuvant and chemopreventive therapy despite the predominantly negative estrogen receptor status of BRCA1 breast cancers. The distinctive biology of BRCA1 and BRCA2 breast cancers bodes well for the development of...
Source: Women's Health Weekly (2008-04-24)
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