Women's Health Weekly
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of Women's Health Weekly
We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.
Breast Cancer
Researchers from INSERM report recent findings in breast cancer
April 24th, 2008
"WISP-2/CCN5 is an estrogen-regulated member of the ''connective tissue growth factor/cysteine-rich 61/ nephroblastoma overexpressed'' (CCN) family of the cell growth and differentiation regulators. The WISP-2/ CCN5 mRNA transcript is undetectable in normal human mammary cells, as well as in highly aggressive breast cancer cell lines, in contrast with its higher level in the breast cancer cell lines characterized by a more differentiated phenotype," scientists in Paris, France report. "We report here that knockdown of WISP-2/CCN5 by RNA interference in estrogen receptor alpha (ER alpha)-positive MCF-7 breast cancer cells induced an estradiol-independent growth linked to...
Source: Women's Health Weekly (2008-04-24)
|
