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Women's Health Weekly

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Breast Cancer



Researchers from University of Toronto detail findings in breast cancer



April 24th, 2008

According to recent research from Toronto, Canada, " There have been no studies to date which look at the relative effectiveness of different regimens of chemotherapy in women who have breast cancer and who carry a BRCA1 germ-line mutation. We wished to compare rates of response to neo-adjuvant chemotherapy in BRCA1 mutation carriers and non-carrier controls."

"Experimental design From a registry of 3,479 patients, we identified 44 Polish women who carried a BRCA1 founder mutation and who had been treated with neo-adjuvant chemotherapy for breast cancer, and 41 age- and hospital-matched controls. Results 35 of the 44 BRCA1 mutation carriers (80%) experienced a partial...


Source: Women's Health Weekly (2008-04-24)

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