Women's Health Weekly
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Breast Cancer
Study findings from M. Kammori et al broaden understanding of breast cancer
April 24th, 2008
"An accurate investigation of the HER2 protooncogene is extremely important for the therapy and prognostication of breast cancer. Currently, immunohistochemistry (IHC) and fluorescence in situ hybridization (FISH) are standard methods for this purpose," scientists in Tokyo, Japan report. "The aim of this study was to detect the expression and amplification of HER2 in paraffin-embedded samples of breast cancer tissue and to investigate the relationship between HER2 amplification and various clinicopathological parameters in advanced breast cancers. We used FISH to examine the HER2 gene amplification and IHC to examine the expression of HER2 protein, estrogen receptor...
Source: Women's Health Weekly (2008-04-24)
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