Women's Health Weekly
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Breast Cancer
Findings from F.C. Bidard and co-authors broaden understanding of breast cancer
May 1st, 2008
"At metastatic relapse, detection of circulating tumor cells (CTC) in peripheral blood is predictive of poor survival of breast cancer patients. Detection of disseminated tumor cells (DTC) in bone marrow (BM) is an independent prognostic factor in early breast cancer," researchers in Paris, France report. "We evaluated the prognostic value of DTC detection in the BM of metastatic breast cancer patients. BM aspirates from 138 patients were screened for DTC with the pancytokeratin mAb A45-B/B3, according to the ISHAGE classification. One hundred and ten patients (80%) were enrolled before first-line treatment. Thirty-seven patients were simultaneously screened for CTC in...
Source: Women's Health Weekly (2008-05-01)
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