Women's Health Weekly
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Breast Cancer
Reports on breast cancer findings from S. Sinha and co-researchers provide new insights
May 1st, 2008
According to recent research published in the journal Annals of Surgical Oncology, "This study attempts to understand the association of candidate tumour suppressor genes SH3GL2, CDKN2A (p16-p14) and CDKN2B (p15) in development of early-onset (group A) and late-onset (group B) breast carcinoma (BC). Deletion, methylation, and mutation of the candidate tumour suppressor genes (TSGs) were analysed in 47 group A and 59 group B samples." "Immunohistochemical analysis was used to identify the expression status of SH3GL2 and p16. Clinicopathological correlation of the alterations was analysed by the chi-square and log-rank tests. Higher frequency of overall alterations...
Source: Women's Health Weekly (2008-05-01)
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