Women's Health Weekly
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Breast Cancer
Research from T. Garcia and co-researchers yields new findings on breast cancer
May 1st, 2008
According to recent research from Romainville, France, "Breast cancer patients with advanced disease exhibit bone metastases, leading to the formation of osteolytic lesions for which the only currently available treatments are palliative. Here, we describe how we refined a mouse model of human breast cancer metastasis into bone, characterized its transcriptome and demonstrated its clinical relevance." "Cells were selected from bone metastases caused by MDA-MB-231 cells after several in vivo passages, and engineered to express luciferase. Whole body bioluminescence live imaging indicated that the selected isogenic B02 clone was unique in its ability to form rapidly...
Source: Women's Health Weekly (2008-05-01)
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