Women's Health Weekly
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Breast Cancer
Researchers from Charles University, Medical Department report on findings in breast cancer
May 1st, 2008
"The prognosis of patients with BRCA1-related breast carcinomas is inferior to the patients without BRCA1 mutation, but most of these tumors have a so-called triple negative phenotype characterized by increased chemosensitivity. Information regarding the chemosensitivity of BRCA1-related breast carcinomas is limited," investigators in Czech Republic report. "We present a case of a mother and daughter with hereditary breast carcinoma treated with primary chemotherapy using the dose-dense combination of doxorubicin and cyclophosphamide and sequential weekly paclitaxel administration. Pathological complete response was observed in both patients. Subsequent genetic analysis...
Source: Women's Health Weekly (2008-05-01)
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