Women's Health Weekly
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Breast Cancer
Researchers from National University describe findings in breast cancer
May 1st, 2008
"The human epidermal growth factor receptor type 2 (HER-2/neu) oncoprotein is over-expressed in about 30% of breast cancers and associates with metastatic phenotypes of breast tumours. Dissecting the HER-2/neu-modulated molecules in cancer will be helpful in elucidating the underlying molecular mechanisms of HER-2/neu-driven tumourigenesis," scientists writing in the journal Proteomics Clinical Applications report. "We investigated the differential proteome profiles between microdissected HER-2/neu-positive and -negative tumours and unambiguously identified 21 proteins with diverse biological functions by peptide sequencing and NCBlnr database interrogation. Six...
Source: Women's Health Weekly (2008-05-01)
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