Women's Health Weekly
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Breast Cancer
Studies conducted at Kurume University on breast cancer recently published
May 1st, 2008
"In our present study, we examined whether nuclear localization of Y-box binding protein-1 (YB-1) is associated with the expression of epidermal growth factor receptors (EGFR), hormone receptors, and other molecules affecting breast cancer prognosis. The expression of nuclear YB-1, clinicopathologic findings, and molecular markers [EGFR, HER2, estrogen receptor (ER)alpha, ER beta, progesterone receptor, chemokine (C-X-C motif) receptor 4 (CXCR4), phosphorylated Akt, and major vault protein/lung resistance protein] were immunohistochemically analyzed," investigators in Kurume, Japan report. "The association of the expression of nuclear YB-1 and the molecular markers was...
Source: Women's Health Weekly (2008-05-01)
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