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Women's Health Weekly

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Breast Cancer



Study results from Duke University, Medical Department broaden understanding of breast cancer



May 1st, 2008

"Premenopausal women treated for early stage breast cancer (ESBC) are at risk for chemotherapy-related amenorrhea (CRA). Prospectively-validated, predictive markers of CRA are needed," investigators in the United States report.

"Premenopausal women with ESBC and planned chemotherapy (>= 25% risk of amenorrhea) were evaluated. Follicle stimulating hormone (FSH), estradiol, Inhibin A and B, anti-Mllerian hormone (AMH), and quality of life (QOL) were prospectively evaluated pre-, post-, 6 months and 1 year post-chemotherapy and correlated with age and menstrual status. CRA was defined as absence of menses 1 year post-chemotherapy. Forty-four women were evaluated at the...


Source: Women's Health Weekly (2008-05-01)

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