Women's Health Weekly
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Breast Cancer
Research on breast cancer discussed by L. Norton and co-researchers
May 8th, 2008
"Theoretical analyses and theory-motivated laboratory experiments have confirmed that for anti-mitotic drugs administered by bolus the inter-treatment interval is a critical determinant of ultimate success. Maximum cell kill is best achieved by using the optimal (not necessarily the maximum tolerated) dose level as often as feasible considering the impact of the drug on host toxicity," investigators in the United States report. "This approach has been termed 'dose density', which captures the concept of optimally frequent administration. The feasibility and non-comparative efficacy of the application of this concept was developed in a series of clinical trials at...
Source: Women's Health Weekly (2008-05-08)
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