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Hormones

Study data from University of Utah, ARUP Institute for Clinical and Experimental Pathology provide new insights into hormones in children

Published in Women's Health Weekly, May 8th, 2008

New investigation results, 'High-sensitivity tandem mass spectrometry assay for serum estrone and estradiol,' are detailed in a study published in American Journal of Clinical Pathology. According to recent research from the United States, "High-sensitivity measurement of serum estrogens is important in adult and pediatric endocrinology and oncology. We developed a high-sensitivity liquid chromatography-tandem mass spectrometry (LC-MS/MS) assay for simultaneous measurement of estrone (E1) and estradiol (E2)."

"Aliquots of 200 muL of serum were spiked with internal standard, extracted, derivatized with dansyl chloride, and analyzed by LC-MS/MS using 2-dimensional...

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