Women's Health Weekly
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Breast Cancer
Studies from Y.X. Zhang et al provide new data on breast cancer
May 8th, 2008
According to recent research from Martinsried, Germany, "Protein kinases play important roles in tumor development and progression. A variety of members of this family of signal transduction enzymes serve as targets for therapeutic intervention in cancer." "We have identified the receptor tyrosine kinase (RTK) AXL as a potential mediator of motility and invasivity of breast cancer cells. AXL is expressed in most highly invasive breast cancer cells, but not in breast cancer cells of low invasivity. Ectopic expression of AXL was sufficient to confer a highly invasive phenotype to weakly invasive MCF7 breast cancer cells. Experimental inhibition of AXL signaling by a...
Source: Women's Health Weekly (2008-05-08)
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