Women's Health Weekly
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Cancer
New cancer study results from University of Regensburg described
May 8th, 2008
According to recent research published in the journal Cancer Science, "Nephronectin (POEM) was originally identified as a factor involved in tissue morphogenesis. POEM has several characteristics of a matrix protein including an arg-gly-asp binding domain site that is recognized by integrins." "Recently, deregulation of POEM was found in breast cancer. We therefore speculate that deregulation of POEM expression plays a role in the development or progression of malignant melanoma. Thus, we evaluated melanoma cell lines and tissue samples of malignant melanoma for POEM transcription. We found that POEM expression was reduced or lost in most cell lines and in all...
Source: Women's Health Weekly (2008-05-08)
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