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Women's Health Weekly

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Breast Cancer



New breast cancer study findings have been reported from P. Biron et al



May 15th, 2008

"Pegase 03 is a multicenter prospective randomized phase III trial evaluating the impact of first-line high-dose chemotherapy (HDC) with stem cell support on overall survival (OS), disease-free survival (DFS) and response rate in 308 patients with histologically proven metastatic breast cancer responding to induction therapy. Eligible patients received four induction cycles with FEC 100 (5-fluorouracil 500mg/m(2), epirubicin 100 mg/m(2), cyclophosphamide 500 mg/m(2))," scientists writing in the journal Bone Marrow Transplantation report.

"Patients with objective response (N=179) were randomized to one cycle of HDC (cyclophosphamide 6000 mg/m2 and thiotepa 800...


Source: Women's Health Weekly (2008-05-15)

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