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Women's Health Weekly

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Breast Cancer



New breast cancer study findings reported from Mayo Clinic



May 15th, 2008

" The cyclooxygenase-2 (COX-2) enzyme, which is induced by inflammatory and mitogenic stimuli, plays a protumorigenic role in several human cancers. COX-2 is overexpressed in invasive and in situ breast cancers," scientists writing in the Journal of the National Cancer Institute report.

"Atypical hyperplasia in breast tissue, although benign, is associated with a high risk of breast cancer. We investigated whether COX-2 overexpression in atypical hyperplasia is associated with the risk of subsequent breast cancer. COX-2 expression was assessed immunohistochemically in archival sections from 235 women with atypia whose biopsy specimens were obtained at the Mayo...


Source: Women's Health Weekly (2008-05-15)

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