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Breast Cancer

Research reports from Vanderbilt University provide new insights into breast cancer

Published in Women's Health Weekly, May 15th, 2008

According to a study from the United States, " To administer the epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor erlotinib to patients with operable untreated breast cancer during the immediate preoperative period and to measure an antiproliferative and/or a proapoptotic effect in the post-therapy specimen and determine a biomarker profile associated with evidence of erlotinib-mediated cellular activity. Patients and Methods Newly diagnosed patients with stages I to IIIA invasive breast cancer were treated with erlotinib 150 mg/d orally for 6 to 14 days until the day before surgery."

"Erlotinib plasma levels were measured by tandem mass spectrometry...

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