Women's Health Weekly
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Breast Cancer
Data on breast cancer detailed by A.D. Seidman and co-authors
May 22nd, 2008
According to recent research published in the Journal of Clinical Oncology, " Phase II trials suggested that weekly paclitaxel might be more effective and less toxic than every-3-weeks administration for metastatic breast cancer (MBC). Cancer and Leukemia Group B (CALGB) protocol 9840 was initiated to address this question." "Subsequently trastuzumab was demonstrated to improve outcomes of paclitaxel therapy for human epidermal growth factor receptor-2 (HER-2)-positive patients, and was therefore incorporated. Because inhibition of HER-family signaling had potential efficacy even without HER-2 overexpression, we randomly assigned for trastuzumab in this...
Source: Women's Health Weekly (2008-05-22)
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