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Women's Health Weekly

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Breast Cancer



Findings from J.M. Dixon and co-researchers advance knowledge in breast cancer



May 22nd, 2008

" To compare the effects of anastrozole and letrozole on plasma estradiol (E2) and estrone sulfate (E1S) levels. Patients and Methods Fifty-four postmenopausal women with estrogen receptor-positive breast cancer receiving aromatase inhibitors (AIs) as part of their adjuvant therapy were randomly assigned to receive either 3 months of anastrozole (1 mg) followed by 3 months of letrozole (2.5 mg), both given orally once daily, or 3 months of the opposite sequence," investigators in Scotland report.

"Blood was taken at the same time and the same day of the week from each patient, before and after 3 months of each drug, and plasma levels of E2 and E1S were determined using...


Source: Women's Health Weekly (2008-05-22)

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