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Women's Health Weekly

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Breast Cancer



Research from Ohio State University in breast cancer provides new insights



May 22nd, 2008

According to recent research from the United States, " An anthracycline-based combination followed by, or combined with, a taxane is the sequence used in most adjuvant chemotherapy regimens. We hypothesized that administering the taxane before the anthracycline combination would be associated with fewer dose reductions and delays than the reverse sequence."

"To test this hypothesis, a randomized phase II multicenter adjuvant chemotherapy trial was performed. Patients and Methods Fifty-six patients with axillary node-positive, nonmetastatic breast cancer were randomly assigned either to group A (docetaxel [DOC] 75 mg/m(2) intravenously [IV] every 14 days for four cycles...


Source: Women's Health Weekly (2008-05-22)

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