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Women's Health Weekly

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Breast Cancer



Research in the area of breast cancer reported from A. Ravaioli and colleagues



May 22nd, 2008

According to recent research from Italy, "Low p27 and high Skp2 immunoreactivity are associated with a poor prognosis and other poor prognostic features including resistant phenotypes and antiestrogen drug resistance. We investigated these proteins in two International Breast Cancer Study Group trials studying node-negative early breast cancer."

"Trial VIII compared chemotherapy followed by goserelin with either modality alone in premenopausal patients. Trial IX compared chemotherapy followed by tamoxifen with tamoxifen alone in postmenopausal patients. Central Pathology Office assessed p27 and Skp2 expression in the primary tumor by immunohistochemistry among 1631...


Source: Women's Health Weekly (2008-05-22)

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