Dana-Farber Cancer Institute

Cells lining milk ducts hold key to spread of common form of breast cancer

Published in Women's Health Weekly, May 22nd, 2008

BOSTON--When a form of cancer that begins in the milk ducts of the breast invades neighboring tissue to spread to other parts of the body, the cause lies not in the tumor cells themselves but in a group of abnormal surrounding cells that cause the walls of the duct to deteriorate like a rusty pipe, according to a new study led by Dana-Farber Cancer Institute researchers.

The discovery, reported in the May 6 issue of Cancer Cell, may lead to screening tests to determine whether the disease -- known as ductal carcinoma in situ, or DCIS -- is likely to spread beyond the ducts, based on genetic abnormalities in cells in the ducts' lining. And it sets the stage for...

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Source: Women's Health Weekly (2008-05-22)

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