Women's Health Weekly
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Cancer
Researchers at Comenius University, Medical Department target cancer
May 22nd, 2008
"Single - agent therapy with aromatase inhibitors has no established role in premenopausal women with breast cancer. In this study, tumor suppressive effects of letrozole in the prevention of N-methyl-N-nitrosourea - induced mammary carcinogenesis in female Sprague-Dawley rats were evaluated," researchers in Martin, Slovakia report. "Letrozole was dietary administered in two concentrations - I mg/1 kg (LETRO 1), and 10 mg/1 kg (LETRO 10). Letrozole suppressed incidence of mammary gland cancer by 93 % (P <0.00002) in the group LETRO I in comparison with control animals. Total suppression of mammary carcinogenesis was observed in the group LETRO 10. In the groups with...
Source: Women's Health Weekly (2008-05-22)
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