Women's Health Weekly
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Breast Cancer
Data from INSERM advance knowledge in breast cancer
May 29th, 2008
According to a study from Paris, France, "Environmental chemicals may affect human health by disrupting endocrine function. Their possible role in the mammary gland and breast tumors is still unknown." "Previous studies have demonstrated that vascular endothelial growth factor (VEGF), a key factor in angiogenesis and tumor progression, is an estrogen-regulated gene. We analyzed whether VEGF expression is regulated by different xenoestrogens in several breast cancer cells, MELN (derived from MCF-7) and MELP (derived from MDA-MB-231) and stably expressing estrogen receptor alpha (ER alpha); these cell lines stably express estrogen response element (beta-globin)luciferase....
Source: Women's Health Weekly (2008-05-29)
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