Women's Health Weekly
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Breast Cancer
New breast cancer study findings have been published by scientists at Research Center
May 29th, 2008
"Recent studies have demonstrated a direct involvement of B7-H1, PD-1 and FOXP3 molecules in the immune escape of cancer. B7-H1 is an inhibitory molecule that binds to PD-1 on T lymphocytes, while FOXP3 is a marker for regulatory T cells (T-regs)," scientists in Riyadh, Saudi Arabia report. "We have previously demonstrated the association of B7-H1-expressing T infiltrating lymphocytes (TIL) with high-risk breast cancer patients while other studies reported the involvement of FOXP3+ T-regs as a bad prognostic factor in breast tumors. Although the co-existence between the two types of cells has been demonstrated in vitro and animal models, their relative infiltration and...
Source: Women's Health Weekly (2008-05-29)
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