Women's Health Weekly
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Breast Cancer
Recent studies by K. Einarsdottir and co-authors add new data to breast cancer findings
May 29th, 2008
According to a study from Singapore, Singapore, " Oestrogen exposure is a central factor in the development of breast cancer. Oestrogen receptor alpha ( ESR1) is the main mediator of oestrogen effect in breast epithelia and has also been shown to be activated by epidermal growth factor ( EGF)." "We sought to determine if common genetic variation in the ESR1 and EGF genes affects breast cancer risk, tumour characteristics or breast cancer survival. We genotyped 157 single nucleotide polymorphisms ( SNPs) in ESR1 and 54 SNPs in EGF in 92 Swedish controls and selected haplotype tagging SNPs ( tagSNPs) that could predict both single SNP and haplotype variation in the genes...
Source: Women's Health Weekly (2008-05-29)
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