Women's Health Weekly
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Breast Cancer
Research from M. Renz and co-researchers provides new data on breast cancer
May 29th, 2008
"The CapG protein, a Gelsolin-related actin-binding protein, is expressed at higher levels in breast cancer, especially in metastasizing breast cancer, than in normal breast epithelium. Furthermore, it is known that an increased expression of the CapG protein triggers an increase in cell motility," investigators in Heidelberg, Germany report. "According to in vitro experiments, it was supposed that it is the nuclear fraction of the protein, which causes the increase in cell motility. Here, we examined the dynamical distribution of the CapG protein within the living cell, i.e. the import of the CapG protein into the nucleus. The nuclear import kinetics of invasive,...
Source: Women's Health Weekly (2008-05-29)
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