Women's Health Weekly
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Breast Cancer
Research results from R. Vaclavikova and colleagues update understanding of breast cancer
May 29th, 2008
According to recent research published in the journal Pharmacogenetics and Genomics, "Objectives Resistance of tumor cells to multiple cytostatic agents is one of the major impediments of successful cancer chemotherapy. A large part of resistance of tumors to chemotherapy is caused by the ABC transporter P-glycoprotein encoded by the ABCB1 gene." "The main aim of this study was to assess the prognostic value of ABCB1 genotype and phenotype in breast cancer. Six ABCB1 single nucleotide polymorphisms (SNPs) were determined in 90 Czech breast cancer patients by a novel method that allows simultaneous assessment of multiple polymorphisms on a single electronic...
Source: Women's Health Weekly (2008-05-29)
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