Women's Health Weekly
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Breast Cancer
New breast cancer study findings have been published by scientists at Cheju National University
June 5th, 2008
In this recently published article, scientists in South Korea conducted a study "To investigate whether subtoxic concentration of beta-sitosterol (SITO) combined with TNF-related apoptosis-inducing ligand (TRAIL) induces apoptosis in TRAIL-resistant MDA-MB-231 breast cancer cells. Cell viability and growth were assessed by 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphnyl-2H-tetrazolim bromide assays, chromatin condensation, release of lactate dehydrogenase (LDH), and Annexin V+ cells." "The apoptosis-related proteins were detected by Western blotting. Treatment with TRAIL in combination with subtoxic concentrations of SITO sensitized MDA-MB-231 breast cancer cells to...
Source: Women's Health Weekly (2008-06-05)
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