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Women's Health Weekly

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JAMA and Archives Journals



Higher oxidized LDL levels associated with increased risk of metabolic syndrome



June 5th, 2008

Higher concentrations of low-density lipoprotein (LDL) that has been modified by oxidation is associated with an increased incidence of abdominal obesity, high fasting glucose levels and high triglyceride levels and the metabolic syndrome, which includes a combination of these conditions, according to a study in the May 21 issue of JAMA.

Studies in cellular and animal models have suggested that oxidized LDL (small fraction of LDL, the so called "bad" cholesterol, that has undergone oxidation) contributes to processes that lead to the incidence of the metabolic syndrome. However, this association has not been tested in humans, according to background information in the...


Source: Women's Health Weekly (2008-06-05)

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