Women's Health Weekly
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Breast Cancer
Research from Baylor College of Medicine, College of Medicine broadens understanding of breast cancer
June 5th, 2008
According to recent research from the United States, "Retinoids, vitamin A analogues that bind to retinoic acid receptor (RAR) or retinoid X receptor (RXR), play important roles in regulating cell proliferation, apoptosis, and differentiation. Recently, RXR-selective ligands, also referred to as rexinoids, have been investigated as potential chemopreventive agents for breast cancer." "Our previous studies demonstrated that the rexinoid bexarotene significantly prevented ER-negative mammary tumourigenesis with less toxicity than naturally occurring retinoids in animal models. To determine whether bexarotene prevents cancer at the early stages during the multistage...
Source: Women's Health Weekly (2008-06-05)
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