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Women's Health Weekly

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Breast Cancer



Research on breast cancer detailed by T. Osako and co-authors



June 5th, 2008

" We retrospectively evaluated the efficacy and safety of combination therapy of trastuzumab plus capecitabine in heavily pretreated patients with HER2- positive metastatic breast cancer (MBC). Patients with HER2- positive MBC who had been administered the combination therapy between July 2003 and July 2006 at the Cancer Institute Hospital, Tokyo, were retrospectively reviewed," investigators in Tokyo, Japan report.

"Capecitabine (828 mg/m(2)) was given twice daily for 3 weeks followed by a 1-week rest period; this was repeated every 4 weeks. Trastuzumab was given at 4 mg/kg as an initial loading dose intravenously, followed by 2 mg/kg weekly. We investigated objective...


Source: Women's Health Weekly (2008-06-05)

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