Women's Health Weekly
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Breast Cancer
Research on breast cancer published by L.C. Sakoda et al
June 5th, 2008
"Enzymes encoded by the glutathione S-tranferase mu 1 (GSTM1) and pi 1 (GSTP1) genes, which are expressed in breast tissue, catalyze the detoxification of endogenous and exogenous electrophiles. Reduced enzyme activity, due to carriage of the GSTM1 deletion or the GSTP1 Ile105Val Val allele, may therefore affect susceptibility to breast cancer and related conditions," scientists in the United States report. "In a case-control study of Chinese women, we examined whether these polymorphisms were associated with risk of breast cancer and fibrocystic breast conditions. Women diagnosed with breast cancer (n = 615) or fibrocystic breast conditions (n = 467) were compared to...
Source: Women's Health Weekly (2008-06-05)
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