Women's Health Weekly
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Breast Cancer
New breast cancer study findings have been reported by R.X. Yang and colleagues
June 12th, 2008
"Ultraconserved elements (UCEs) are segments of >200 bp length showing absolute sequence identity between orthologous regions of human, rat and mouse genomes. The selection factors acting on these UCEs are still unknown," scientists in Heidelberg, Germany report. "Recent studies have shown that UCEs function as long-range enhancers of flanking genes or are involved in splicing when overlapping with exons. The depletion of UCEs among copy number variation as well as the significant under-representation of single-nucleotide polymorphisms (SNPs) within UCEs have also revealed their evolutional and functional importance indicating their potential impact on disease, such...
Source: Women's Health Weekly (2008-06-12)
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