Women's Health Weekly
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Breast Cancer
Studies from Nanjing Medical University in the area of breast cancer described
June 12th, 2008
"The novel tumor suppressor RASSF1A is frequently inactivated during human tumorigenesis by promoter methylation. In this study, we detected the RASSF1A promoter methylation by methylated-specific PCR and investigated RASSF1A gene expression by semi-quantitative RT-PCR and inummohistochemical staining in 36 cases of breast cancer and their adjacent normal tissues in Chinese women," scientists in Nanjing, People's Republic of China report. "The promoter methylation of the RASSF1A gene was found to be a frequent event in the breast cancers (61.1%). RASSF1A methylation was not found in the matched adjacent normal tissues. The loss frequency of RASSF1A mRNA was 33.3% and...
Source: Women's Health Weekly (2008-06-12)
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