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Women's Health Weekly

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Breast Cancer



Study results from Case Western Reserve University, Medical Department update understanding of breast cancer



June 12th, 2008

"Aneuploidy and genomic instability are common features of human cancers, including breast cancer; however, mechanisms by which such abnormalities develop are not understood. The exquisite dependence of the mammary gland on hormones for growth and development as well as hormonal contributions to breast cancer risk and progression suggest that tumorigenic mechanisms in the breast should be considered in the context of hormonal stimulation," investigators in the United States report.

"We used transgenic mice that overexpress luteinizing hormone with subsequent ovarian hyperstimulation as a model to identify mechanisms involved in hormone-induced mammary cancer. Tumor...


Source: Women's Health Weekly (2008-06-12)

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