Women's Health Weekly
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Carcinoma
Research in the area of carcinoma reported from N. Hafner and colleagues
June 12th, 2008
According to recent research from Jena, Germany, "Virus integration into the host genome is a characteristic step during cervical carcinogenesis. Experimental data provide evidence that integration could result in increased levels of oncogene (E6/E7) transcripts." "This is the first study in which the level of viral transcripts is correlated to the physical state of the viral genome in cervical intraepithelial neoplasia (CIN) and cervical carcinomas (CxCa). Using the APOT-assayinteg rate-derived transcripts only were detected in 3/28 (11%) CIN and in 28/55 (51%) carcinomas, respectively. The remaining biopsies contained either episome-derived transcripts only or both...
Source: Women's Health Weekly (2008-06-12)
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