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Women's Health Weekly

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Amgen



Denosumab Achieved Superior Bone Mineral Density Gains in Head-to-Head Trial versus Weekly Alendronate FOSAMAX



June 12th, 2008

Amgen (NASDAQ: AMGN) announced complete results from a head-to-head, double-blind study comparing the effects of twice-yearly subcutaneous injections of denosumab versus weekly oral doses of alendronate (FOSAMAX(R)) on bone mineral density (BMD) in postmenopausal women with low BMD. The results were presented during a late breaking session at this year's 35th Annual European Symposium on Calcified Tissues (ECTS) meeting. Top-line results of this study were previously reported in January 2008.

In the non-pivotal Phase 3 study, administration of denosumab resulted in significantly greater BMD gains at all sites measured, compared with alendronate.

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Source: Women's Health Weekly (2008-06-12)

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