Women's Health Weekly
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Breast Cancer
Recent findings in breast cancer described by R.L. Milne and colleagues
June 26th, 2008
"It is not clear that the published estimates of the breast and ovarian cancer penetrances of mutations in BRCA1 and BRCA2 can be used in genetic counseling in countries such as Spain, where the incidence of breast cancer in the general population is considerably lower, the prevalence of BRCA2 mutations seems to be higher, and a distinct spectrum of recurrent mutations exists for both genes. We aimed to estimate these penetrances for women attending genetic counseling units in Spain," scientists in Madrid, Spain report. "We collected phenotype and genotype data on 155 BRCA1 and 164 BRCA2 mutation carrier families from 12 centers across the country. Average age-specific...
Source: Women's Health Weekly (2008-06-26)
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