Women's Health Weekly
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Breast Cancer
Reports from University of Naples describe recent advances in breast cancer
June 26th, 2008
"Microarray-based gene expression profiling is well suited for parallel quantitative analysis of large numbers of RNAs, but its application to cancer biopsies, particularly formalin-fixed, paraffin-embedded (FFPE) archived tissues, is limited by the poor quality of the RNA recovered. This represents a serious drawback, as FFPE tumor tissue banks are available with clinical and prognostic annotations, which could be exploited for molecular profiling studies, provided that reliable analytical technologies are found," researchers in Naples, Italy report. "We applied and evaluated here a microarray-based cDNA-mediated annealing, selection, extension and ligation (DASL)...
Source: Women's Health Weekly (2008-06-26)
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