Women's Health Weekly
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Breast Cancer
Research from Y. Cui et al broadens understanding of breast cancer
June 26th, 2008
"In our study we use nordihydroguaiaretic acid (NDGA), the naturally occurring lignan, to investigate whether it plays a role in the prevention and treatment of cancer by epigenetic modifications. The growth inhibitory effect of NDGA on human breast cancer cell lines was determined using the MTT assay (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide assay)," researchers in Beijing, People's Republic of China report. "It substantially inhibited the growth of human breast cancer cell lines SKBR3 and MDA-MB-435 with an estimated IC50 of 31.09 +/- 1.6 and 38.8 +/- 2.1 mu mol/l respectively, after 4 days incubation with different NDGA concentrations. The...
Source: Women's Health Weekly (2008-06-26)
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