Women's Health Weekly
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Breast Cancer
Scientists at Cardiff University, Medical Department discuss research in breast cancer
June 26th, 2008
"N-WASP is a key regulator of cell migration and actin polymerisation. We examined the correlation of N-WASP, with human breast cancer, in vitro, in vivo and in clinical breast cancer tissue," investigators in Wales report. "Immunohistochemical study of frozen sectioned human breast mammary tissues (n = 124) revealed that mammary epithelial cells stained positively for N-WASP and that cancer cells in tumour tissues stained very weakly. Quantitative RT-PCR revealed that breast cancer tissues had significantly lower levels of N-WASP compared with normal background mammary tissues (0.83 +/- 0.3 vs 13.6 +/- 13, P = 0.03). Although no significantly correlation was found with...
Source: Women's Health Weekly (2008-06-26)
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