Women's Health Weekly
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Breast Cancer
Findings from A. Urruticoechea and co-authors provide new insights into breast cancer
July 3rd, 2008
" Changes in breast cancer cell biology following hormonal treatment have been claimed as promising predictor markers of clinical benefit even outperforming clinical response. From previous work we selected 10 genes showing both a well known regulation by oestrogen and a high level of early transcriptional regulation following therapy with aromatase inhibitors," researchers in Barcelona, Spain report. "Here we use an animal breast cancer model to explore the feasibility of the determination of their expression in minimally invasive samples and to further assess the magnitude of their regulation by letrozole. Animal and methods Aromatase inhibitor sensitive breast cancer...
Source: Women's Health Weekly (2008-07-03)
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