Women's Health Weekly
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Breast Cancer
New findings from M. Vecchi and co-authors in the area of breast cancer published
July 3rd, 2008
"Metastases have been widely thought to arise from rare, selected, mutation-bearing cells in the primary tumor. Recently, however, it has been proposed that breast tumors are imprinted ab initio with metastatic ability," investigators in Milan, Italy report. "Thus, there is a debate over whether 'phenotypic' disease progression is really associated with 'molecular' progression. We pro. led 26 matched primary breast tumors and lymph node metastases and identified 270 probesets that could discriminate between the two categories. We then used an independent cohort of breast tumors (81 samples) and unmatched distant metastases (32 samples) to validate and re. ne this list...
Source: Women's Health Weekly (2008-07-03)
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