Published in Women's Health Weekly, July 3rd, 2008
"We hypothesized that decreased CDKNIC may be involved in human breast carcinogenesis in vivo. We determined rates of allele imbalance or loss of heterozygosity ( AI/LOH) in CDKNIC, using an intronic polymorphism, and in the surrounding II p15.5 region in 82 breast cancers. We examined the CDKNIC mRNA level in 10 cancers using quantitative real-time PCR (...
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